BDBM50199062 1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-phenylisoquinoline-3-carbonitrile::CHEMBL214876

SMILES COc1ccc2c(NC[C@H](O)CO)nc(C#N)c(-c3ccccc3)c2c1

InChI Key InChIKey=KHVLDRZIYXBOLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199062   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199062(1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199062(1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed