BDBM50198579 2-((((S)-6-(4-(4-fluorophenethyl)-2-oxopiperazin-1-yl)-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)(methyl)amino)-3-hydroxy-N,N-dimethylpropanamide::CHEMBL385710

SMILES CN(C)C(=O)C(CO)N(C)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(F)cc2)CC1=O

InChI Key InChIKey=CVRXJUWJTSBTOZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198579   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198579(2-((((S)-6-(4-(4-fluorophenethyl)-2-oxopiperazin-1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198579(2-((((S)-6-(4-(4-fluorophenethyl)-2-oxopiperazin-1...)
Affinity DataKi:  2.70E+5nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed