BDBM50198081 CHEMBL3915550

SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(NC(=O)CCC(O)=O)c2)C(=O)N1C

InChI Key InChIKey=AIYAAHSLCORTFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198081   

TargetAurora kinase A(Human)
University of Berne

Curated by ChEMBL
LigandPNGBDBM50198081(CHEMBL3915550)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
University of Berne

Curated by ChEMBL
LigandPNGBDBM50198081(CHEMBL3915550)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed