BDBM50198034 CHEMBL376557::[(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-methyl-propyl]-phosphonic acid

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1)P(O)(O)=O

InChI Key InChIKey=BUKCBCDGRPOFJP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50198034   

TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 47nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 28nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 77nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198034([(R)-1-(4'-chloro-biphenyl-4-sulfonylamino)-2-meth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed