BDBM50197996 3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-pyrazol-5-yloxy)-N-(6-(diethylamino)hexan-3-yl)propanamide::CHEMBL391662

SMILES CCC(CCCN(CC)CC)NC(=O)CCOc1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=OJSYDGKOJKXORO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197996   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50: 9nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50: 83nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CCR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed