BDBM50197751 (2E)-2-{2-[(4-chlorobenzyl)oxy]benzylidene}hydrazinecarboximidamide::CHEMBL449045

SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1ccccc1-[#8]-[#6]-c1ccc(Cl)cc1

InChI Key InChIKey=XQLMWPAYSAOCGQ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197751   

TargetC-C chemokine receptor type 5(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50197751((2E)-2-{2-[(4-chlorobenzyl)oxy]benzylidene}hydrazi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5/CD4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFurin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197751((2E)-2-{2-[(4-chlorobenzyl)oxy]benzylidene}hydrazi...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of human recombinant furin by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetFurin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50197751((2E)-2-{2-[(4-chlorobenzyl)oxy]benzylidene}hydrazi...)
Affinity DataKi:  2.53E+4nMAssay Description:Inhibition of soluble human furin using boc-RVRR-MCA as substrate incubated for 45 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed