BDBM50197618 CHEMBL3901030

SMILES Cc1c(NC(=O)Nc2cc(nn2-c2ccccc2)C(F)(F)F)n(nc1-c1cnn(C)c1)-c1ccccc1

InChI Key InChIKey=QJVHIMLGONEYEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197618   

TargetHigh affinity nerve growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50197618(CHEMBL3901030)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged recombinant human TrkA using Alexa-Fluor tracer-236 incubated for 60 mins by TR-FRET based Lantha-screen Eu kinase binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2018
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50197618(CHEMBL3901030)
Affinity DataIC50: 100nMAssay Description:Inhibition of human TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed