BDBM50197486 (2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicyclo[3.2.1]octane-2-carboxylate::CHEMBL390929

SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)c(Cl)c1)O2

InChI Key InChIKey=DHXANQGCRAVCSQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50197486   

TargetSodium-dependent serotonin transporter(Rhesus macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [3H]citalopram from SERT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed