BDBM50196829 CHEMBL3914729

SMILES CS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3c2cc(Cl)cc3Cl)N2CCCNCC2)cc1

InChI Key InChIKey=KNXKSCOYGZWIAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196829   

TargetCytochrome P450 2D6(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196829(CHEMBL3914729)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 3(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50196829(CHEMBL3914729)
Affinity DataIC50: 6nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed