BDBM50196688 CHEMBL224509::N-(1-(4-fluorobenzyl)piperidin-3-yl)-1H-indazol-5-amine::N-[1-(4-fluorobenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine

SMILES Fc1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1

InChI Key InChIKey=LBIZOXVQFGPTIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196688   

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196688(N-(1-(4-fluorobenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196688(N-(1-(4-fluorobenzyl)piperidin-3-yl)-1H-indazol-5-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed