BDBM50196586 CHEMBL401141::N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-phenylbutan-2-yl)-3-(heptan-4-ylsulfonyl)propanamide

SMILES CCCC(CCC)S(=O)(=O)CCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(OC)c1

InChI Key InChIKey=MPGYFTYRJCOSLV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196586   

TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 314nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 596nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 9.67E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed