BDBM50196584 CHEMBL252960::N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-phenylbutan-2-yl)-3-(piperidin-1-ylsulfonyl)propanamide

SMILES COc1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)CCS(=O)(=O)N2CCCCC2)c1

InChI Key InChIKey=QKDILUYNDDDGDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196584   

TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed