BDBM50195936 CHEMBL3612420

SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1

InChI Key InChIKey=VRWIMNXQXLLYDR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195936   

TargetProtease(Human immunodeficiency virus type 1)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of recombinant HIV1 protease using FRET substrate peptide by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataKi:  4.70E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataKi:  3.13E+4nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed