BDBM50194743 CHEMBL214814::diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate::{2-(4-guanidino-phenyl)-1-[(S)-2-((R)-3-hydroxy-2-phenylmethanesulfonylamino-propionylamino)-propionylamino]-ethyl}-phosphonic acid diphenyl ester

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=VCVSFHZQGWZRGK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50194743   

TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of bovine F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194743(diphenyl 1-[(N-alpha-toluenesulfonyl-D-seryl)-L-al...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed