BDBM50194739 CHEMBL213216::diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]-[#6](=O)-c1cccs1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=PISJKIFQWQIHDN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194739   

TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of bovine F10a at 250 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50194739(diphenyl 1-[(N-2-thienyl-D-seryl)-L-alanyl]amino-2...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed