BDBM50194561 CHEMBL375638::N'-{8-fluoro-2-phenyl-3-[4-(tetrahydro-pyran-4-yl)-piperazin-1-ylmethyl]-quinoline-4-carbonyl}-N-phenyl-hydrazinecarboxylic acid methyl ester

SMILES COC(=O)N(NC(=O)c1c(CN2CCN(CC2)C2CCOCC2)c(nc2c(F)cccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=OPNWBWOUADKLSR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194561   

TargetNeuromedin-K receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194561(N'-{8-fluoro-2-phenyl-3-[4-(tetrahydro-pyran-4-yl)...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194561(N'-{8-fluoro-2-phenyl-3-[4-(tetrahydro-pyran-4-yl)...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed