BDBM50194022 5-4-2-fluoro-5-trifluoromethyl)phenoxy)phenylamino)-3-hydroxy-N-1-hydroxypropan-2-yl)isothiazole-4-carboximidamide::CHEMBL217415

SMILES CC(CO)N=C(N)c1c(Nc2ccc(Oc3cc(ccc3F)C(F)(F)F)cc2)s[nH]c1=O

InChI Key InChIKey=AFKUWDZGALVUAF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194022   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194022(5-4-2-fluoro-5-trifluoromethyl)phenoxy)phenylamino...)
Affinity DataEC50:  330nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceuticals Research & Development

Curated by ChEMBL
LigandPNGBDBM50194022(5-4-2-fluoro-5-trifluoromethyl)phenoxy)phenylamino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of MEK-1 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed