BDBM50193548 N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamino)-7,8-dihydronormorphinone

SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccccc1Cl

InChI Key InChIKey=XJIJVLIGDNTFBP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193548   

TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193548(N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamin...)
Affinity DataKi:  0.710nMAssay Description:Stimulation of [35S]GTPgammaS binding to human recombinant MORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193548(N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamin...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]Cl-DPDPE from human recombinant DOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193548(N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamin...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]U-69593 from human recombinant KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed