BDBM50193540 14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodeinone

SMILES COc1ccc2CC3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccc(C)cc1

InChI Key InChIKey=DXMFOUDANJICCW-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193540   

TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  76nMAssay Description:Stimulation of [35S]GTP-gamma-S binding to human recombinant DORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  2.5nMAssay Description:Stimulation of [35S]GTPgammaS binding to human recombinant MORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataEC50:  84nMAssay Description:Stimulation of [35S]GTP-gamma-S binding to human recombinant KORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]Cl-DPDPE from human recombinant DOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50193540(14beta-(4'-methylcinnamoylamino)-7,8-dihydrocodein...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]U-69593 from human recombinant KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed