BDBM50193079 CHEBI:5834::CHEMBL1237210

SMILES CC(C)C(=O)[C@@]12C(O)=C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O

InChI Key InChIKey=IWBJJCOKGLUQIZ-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50193079   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dopamine transporter (unknown origin) assessed as suppression of synaptosomal uptake of dopamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of serotonin transporter (unknown origin) assessed as suppression of synaptosomal uptake of serotoninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of norepinephrine transporter (unknown origin) assessed as suppression of synaptosomal uptake of norepinephrineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Abdul Wali Khan University Mardan

Curated by ChEMBL
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mPGES1 (unknown origin) assessed as reduction in conversion of PGH to PGE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50193079(CHEMBL1237210 | CHEBI:5834)
Affinity DataEC50:  40nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed