BDBM50193073 CHEMBL2397737

SMILES CC1=CCC(=CC1=NC(=O)C1=CC=CC(C1)=N/C(=O)/N=C1/CC(=CC=C1)C(=O)N=C1CC(=CC=C1C)C(=O)N=C1/CC=C(c2cc(cc(c12)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)C(=O)N=C1/CC=C(c2cc(cc(c12)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI Key InChIKey=VTCUUTNDNRAQSK-UHFFFAOYSA-H

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50193073   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of full-length human N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 297nMAssay Description:Inhibition of full-length human N-terminal GST-tagged SIRT1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of sirtuin 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of sirtuin 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sirtuin 3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of sirtuin 5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 297nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of SIRT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed