BDBM50192887 CHEMBL3986947::US10919914, Compound 3626

SMILES C[C@H](NC(=O)c1c(N)ncc2ccccc12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=JUHFRROHHCYSJN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192887   

LigandPNGBDBM50192887(CHEMBL3986947 | US10919914, Compound 3626)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length N-terminal His-tagged PI3Kgamma expressed in Sf9 insect cells using diC8PIP2 as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50192887(CHEMBL3986947 | US10919914, Compound 3626)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged PI3K p110delta/p85alpha coexpressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
LigandPNGBDBM50192887(CHEMBL3986947 | US10919914, Compound 3626)
Affinity DataIC50: 2.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation is used to screen compounds provided herein. This assay uses specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

LigandPNGBDBM50192887(CHEMBL3986947 | US10919914, Compound 3626)
Affinity DataIC50: 3.00E+3nMAssay Description:A PI3-Kinase HTRF assay kit (cat No. 33-016) purchased from Millipore Corporation is used to screen compounds provided herein. This assay uses specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent