BDBM50192686 4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo[2.2.2]octane-1-carboxamide::CHEMBL219606

SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)NC12CCC(CC1)(CC2)C(N)=O

InChI Key InChIKey=LJXXAAVCYKDWBK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50192686   

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192686(4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo...)
Affinity DataIC50: 12.9nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed