BDBM50191839 5-(1-(5-(3-chloro-4-fluorophenyl)pyrimidin-4-yl)piperidin-4-yl)-4-methyl-1H-imidazol-2-amine::CHEMBL211924

SMILES Cc1nc(N)[nH]c1C1CCN(CC1)c1ncncc1-c1ccc(F)c(Cl)c1

InChI Key InChIKey=JMIQKMRPKJYHOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191839   

TargetSodium/hydrogen exchanger 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191839(5-(1-(5-(3-chloro-4-fluorophenyl)pyrimidin-4-yl)pi...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed