BDBM50191817 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cyclopropyl-4-(4-(4-fluorophenyl)piperidin-1-yl)butanamide::CHEMBL214647

SMILES Fc1ccc(cc1)C1CCN(CC[C@@H](C2CC2)C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC1

InChI Key InChIKey=QWTVAFDNGVIQDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191817   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191817((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cycloprop...)
Affinity DataIC50: 72nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in human monocyte cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191817((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-cycloprop...)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed