BDBM50191804 CHEMBL212542::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-methanesulfonamido-4-{spiro[indene-1,4'-piperidine]-1'-yl}butanamide

SMILES CS(=O)(=O)NC(CCN1CCC2(CC1)C=Cc1ccccc21)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QTHFFZVJRFWNKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191804   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191804(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-metha...)
Affinity DataIC50: 244nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed