BDBM50191601 4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone::4-(3-((1H-imidazol-1-yl)methyl)-7-methoxy-4-oxo-4H-chromen-2-yl)benzonitrile::CHEMBL377626

SMILES COc1ccc2c(c1)oc(-c1ccc(cc1)C#N)c(Cn1ccnc1)c2=O

InChI Key InChIKey=MFAAEVRNWGIQOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191601   

TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50191601(4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone | 4...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50191601(4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone | 4...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50191601(4'-cyano-3-(imidazolylmethyl)-7-methoxyflavone | 4...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed