BDBM50191385 (5R,6Z)-6-(6,7-dihydro-4H-pyrazolo[5,1-c]-[1,4]oxazin-2-ylmethylene)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt::CHEMBL377382

SMILES [O-]C(=O)C1=CS[C@H]2N1C(=O)\C2=C\c1cc2COCCn2n1

InChI Key InChIKey=DWYDARUUOLMALM-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191385   

TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191385((5R,6Z)-6-(6,7-dihydro-4H-pyrazolo[5,1-c]-[1,4]oxa...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191385((5R,6Z)-6-(6,7-dihydro-4H-pyrazolo[5,1-c]-[1,4]oxa...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191385((5R,6Z)-6-(6,7-dihydro-4H-pyrazolo[5,1-c]-[1,4]oxa...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetImipenem-hydrolyzing beta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191385((5R,6Z)-6-(6,7-dihydro-4H-pyrazolo[5,1-c]-[1,4]oxa...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Enterobacter cloacae Imi1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed