BDBM50191380 CHEMBL379440::sodium (R,E)-7-oxo-6-((5,6,7,8-tetrahydroimidazo[1,2-a]pyrazin-2-yl)methylene)-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate

SMILES [O-]C(=O)C1=CS[C@H]2N1C(=O)\C2=C/c1cn2CCNCc2n1

InChI Key InChIKey=SZEAVITUDYBJGA-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191380   

TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191380(sodium (R,E)-7-oxo-6-((5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetImipenem-hydrolyzing beta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191380(sodium (R,E)-7-oxo-6-((5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Enterobacter cloacae Imi1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191380(sodium (R,E)-7-oxo-6-((5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191380(sodium (R,E)-7-oxo-6-((5,6,7,8-tetrahydroimidazo[1...)
Affinity DataIC50: 320nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed