BDBM50191327 CHEMBL3960997

SMILES CC(C)c1ccc2C(Cc3ccc(Cl)cc3)C(CC(C)(C)C(O)=O)C(SC(C)(C)C)c2c1

InChI Key InChIKey=SYLBCYQWXLWMGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191327   

TargetDNA polymerase kappa(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191327(CHEMBL3960997)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase kappa(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191327(CHEMBL3960997)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed