BDBM50191271 (4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide::CHEMBL219375::H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2::H-DPhe2-c[Cys3-Phe7-DTrp8-Lys9-Thr10-Cys14]-Thr15-NH2

SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O

InChI Key InChIKey=SGYDRBBPYPDBRO-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50191271   

TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 38nMAssay Description:Inhibition of [125I](Leu8,DTrp22,Tyr25)-SRIF28 binding to human sst3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I](Leu8,DTrp22,Tyr25)-SRIF28 binding to human sst2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I](Leu8,DTrp22,Tyr25)-SRIF28 binding to human sst4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I](Leu8,DTrp22,Tyr25)-SRIF28 binding to human sst1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [125I](Leu8,DTrp22,Tyr25)-SRIF28 binding to human sst5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst4 receptor expressed in chinese hamster CCL39 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst1 receptor expressed in CHOK1 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst5 receptor expressed in CHOK1 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst2 receptor expressed in chinese hamster CCL39 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]-[Leu8, DTrp22, Tyr25]SRIF28 from human sst3 receptor expressed in chinese hamster CCL39 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst3 receptor by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst4 receptor by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst5 receptor by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst1 receptor by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50191271(H-DPhe-c[Cys-Phe-DTrp-Lys-Thr-Cys]-Thr-NH2 | (4R,7...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]LTT-SRIF-28 from human sst2 receptor by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed