BDBM50190112 CHEMBL88808

SMILES NC(CCc1ccccc1)P(O)(=O)CC(Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=STVSJGZHUJJREA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50190112   

TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  10nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  36nMAssay Description:Inhibition of APN in porcine kidney using L-leucine p-nitroanilide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  36nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamyl aminopeptidase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  67nMAssay Description:Inhibition of APA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  67nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  6.47E+3nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed