BDBM50190076 8-chloro-11-(4-methyl-piperazin-1-yl)-5-(toluene-2-sulfonyl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL377452

SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(c2ccccc12)S(=O)(=O)c1ccccc1C

InChI Key InChIKey=NJGQJPYDIXHGGF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190076   

TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190076(8-chloro-11-(4-methyl-piperazin-1-yl)-5-(toluene-2...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190076(8-chloro-11-(4-methyl-piperazin-1-yl)-5-(toluene-2...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed