BDBM50189742 5-[5-(2-hydroxy-5-trifluoromethoxyphenyl)furan-2-ylmethylene]thiazolidine-2,4-dione::CHEMBL211768

SMILES Oc1ccc(OC(F)(F)F)cc1-c1ccc(\C=C2/SC(=O)NC2=O)o1

InChI Key InChIKey=SBGSKEOYYYCTJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189742   

LigandPNGBDBM50189742(5-[5-(2-hydroxy-5-trifluoromethoxyphenyl)furan-2-y...)
Affinity DataIC50: 56nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189742(5-[5-(2-hydroxy-5-trifluoromethoxyphenyl)furan-2-y...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50189742(5-[5-(2-hydroxy-5-trifluoromethoxyphenyl)furan-2-y...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed