BDBM50189631 CHEMBL376983::N-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-yl)acetamide::N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-acetamide

SMILES CC(NC(C)=O)C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1

InChI Key InChIKey=YXGGOPZGTQGTIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189631   

TargetAcetyl-CoA carboxylase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(N-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(N-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(N-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant ACC2 expressed in baculovirus/sf9 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189631(N-(4-(2-(4-phenoxyphenoxy)thiazol-5-yl)but-3-yn-2-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed