BDBM50189444 CHEMBL3827333

SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc2ccc(cc12)S(N)(=O)=O

InChI Key InChIKey=VGQVYKSVLZIXPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189444   

TargetCyclin-dependent kinase 8(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50189444(CHEMBL3827333)
Affinity DataIC50: 43nMAssay Description:Binding affinity to CDK8 (unknown origin) expressed in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetCyclin-C(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50189444(CHEMBL3827333)
Affinity DataIC50: 5.60nMAssay Description:Competitive binding affinity to full length His-tagged human recombinant CDK8/cyclin C expressed in baculovirus after 20 mins in presence of Alexa647...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed