BDBM50188729 CHEMBL3828180

SMILES CN(Cc1nc2c(nc(nc2n1C)-c1ccc2OCOc2c1)N1CCOCC1)c1ncc(cn1)C(=O)NO

InChI Key InChIKey=JSWBEZKWVWBEIP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188729   

TargetHistone deacetylase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50188729(CHEMBL3828180)Copy SMILESCopy InChI

Affinity DataIC50: 0.970nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/10/2017
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50188729(CHEMBL3828180)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system incubated for 1 hr by kinase-g...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/10/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL