BDBM50188565 8-(1-(2-fluoro-3-methylbenzyl)-1H-pyrazol-4-yl)-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione::CHEMBL210609

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cnn(Cc2cccc(C)c2F)c1

InChI Key InChIKey=OPFGSHJNMXTVDA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188565   

TargetAdenosine receptor A2b(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188565(8-(1-(2-fluoro-3-methylbenzyl)-1H-pyrazol-4-yl)-1,...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2b receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188565(8-(1-(2-fluoro-3-methylbenzyl)-1H-pyrazol-4-yl)-1,...)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]CPX from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188565(8-(1-(2-fluoro-3-methylbenzyl)-1H-pyrazol-4-yl)-1,...)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2a receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed