BDBM50188562 1,3-Dipropyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,7H)-dione::CHEMBL380176

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cn[nH]c1

InChI Key InChIKey=FJOWCRNUYDSBQY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188562   

TargetAdenosine receptor A2b(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188562(1,3-Dipropyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2b receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188562(1,3-Dipropyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]CPX from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188562(1,3-Dipropyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50188562(1,3-Dipropyl-8-(1H-pyrazol-4-yl)-1H-purine-2,6(3H,...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2a receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed