BDBM50188097 1-(4-Chlorobenzyl)-1H-imidazole::CHEMBL441367

SMILES Clc1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=RPLWYOLCHGTNSX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50188097   

TargetCytochrome P450 2A6(Human)
TBA

US Patent
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetCytochrome P450 2B6(Human)
TBA

US Patent
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 1.20E+4nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of rat microsomal 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibition of rat testis 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 70nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 46nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Eindhoven University of Technology

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 140nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed