BDBM50187263 (2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2,5-dicarbonitrile::CHEMBL207912

SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N

InChI Key InChIKey=LNZXFOJVAULXCD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50187263   

TargetProlyl endopeptidase FAP(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of APPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of DPP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50187263((2S,5R)-1-[2-(3-hydroxy-adamantan-1-ylamino)-acety...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed