BDBM50187184 2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid::CHEMBL377471

SMILES CC1(C)Cc2c(sc(NC(=O)C(O)=O)c2C(O)=O)C(C)(C)C1

InChI Key InChIKey=CSBSUSFJVLIYMQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187184   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of PTP1B V49A mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed