BDBM50187001 3-(2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione::CHEMBL379438

SMILES Oc1cc(ccc1Nc1c(Nc2ccccc2)c(=O)c1=O)[N+]([O-])=O

InChI Key InChIKey=BGXSRDRXCPKCLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187001   

TargetC-X-C chemokine receptor type 2(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187001(CHEMBL379438 | 3-(2-hydroxy-4-nitrophenylamino)-4-...)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187001(CHEMBL379438 | 3-(2-hydroxy-4-nitrophenylamino)-4-...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Palacky University Olomouc

Curated by ChEMBL
LigandPNGBDBM50187001(CHEMBL379438 | 3-(2-hydroxy-4-nitrophenylamino)-4-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human CXCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed