BDBM50186917 3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid::CHEMBL208168

SMILES Cc1cc(CCC(O)=O)ccc1-c1noc(n1)-c1ccc(cc1)C1CCCCC1

InChI Key InChIKey=VQPXDLUPXBLILC-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186917   

TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186917(3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P2 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186917(3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)...)
Affinity DataEC50:  591nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186917(3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at S1P4 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186917(3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50186917(3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTP-gamma-S uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed