BDBM50186637 3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxylic acid amide::CHEMBL383723

SMILES CNC(=O)Nc1cc(sc1C(N)=O)-c1ccccc1

InChI Key InChIKey=FQHAURJASXHLTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186637   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186637(3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxyli...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186637(3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxyli...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186637(3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxyli...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed