BDBM50186625 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide::CHEMBL207012

SMILES NC(=O)c1sc2ncccc2c1N

InChI Key InChIKey=XZIZYTUIRQMBPN-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50186625   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed