BDBM50186619 3-amino-5-phenyl-thiophene-2-carboxylic acid amide::CHEMBL207028

SMILES NC(=O)c1sc(cc1N)-c1ccccc1

InChI Key InChIKey=DYRYDYQWWQHRQE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50186619   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed