BDBM50186531 CHEMBL379073::cis-N-{3-[(R)-1-(3,5-bis-trifluoromethyl-phenyl)-ethoxymethyl]-3-phenyl-cyclobutyl}-acetamide

SMILES C[C@@H](OC[C@@]1(C[C@@H](C1)NC(C)=O)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZOPRZQRKBZNHLP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186531   

TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186531(cis-N-{3-[(R)-1-(3,5-bis-trifluoromethyl-phenyl)-e...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186531(cis-N-{3-[(R)-1-(3,5-bis-trifluoromethyl-phenyl)-e...)
Affinity DataKi:  2.13E+3nMAssay Description:Displacement of [3H]neurokinin B from human recombinant NK3 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed