BDBM50186483 CHEMBL211021::N-(5-((3-(1-acetylpiperazine-4-carbonyl)benzyloxy)methyl)thiazol-2-yl)-4-tert-butylbenzamide

SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(COCc2cnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2)c1

InChI Key InChIKey=XIABTCSDBYIJTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186483   

TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186483(N-(5-((3-(1-acetylpiperazine-4-carbonyl)benzyloxy)...)
Affinity DataIC50: 930nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed