BDBM50186482 1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)benzoyl)piperazin-1-yl)ethanone::CHEMBL212269

SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(Sc2cnc(Nc3ccccn3)s2)c1

InChI Key InChIKey=ORLXLKYURVKUJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186482   

TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186482(1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50: 690nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50186482(1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50: 240nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed